Chromosomal Microarray Test

Chromosomal Microarray Test

The Microarray Test analyzes the entire genome for over 6,000 known SNPs.

A new approach to genetic testing using microarrays is now available with the launch of DNA Diagnostics’ Microarray test. Microarray tests provide a non-invasive method for analyzing an individual’s genome and detecting chromosomal abnormalities such as translocations, insertions, deletions and duplications. The Microarray Test analyzes the entire genome for over 6,000 known SNPs. The results are used to determine carrier status for certain genetic traits or disorders.

Coverage &
SNP's

The Microarray Test analyzes the entire genome for over 6,000 known SNPs.

25% Discount

Chromosomal Microarray Test cost 22000 Rs after discount

Results

Chromosomal Microarray Test results in 4 weeks

Chromosomal Microarray 750k Test

Test typePediatrician, Physician, Gynecologist
Pre-test InformationDuly filled Genomic Microarray Requisition Form (Form 19) is mandatory.
Report Delivery4 Weeks
Components
Price₹ 22000

What is a Microarray DNA test?

Microarray DNA test is a genomics technology which used to find multiple gene sequences and locations with better precision at a much faster speed compared to other technologies like PCR, QPCR (qualitative Polymerase Chain Reaction).
Microarray means a very small arrangement. The array is created using multiple copies of the genes on a glass slide, with each array contributing hundreds and thousands of genes at a single location which are in form of both horizontal and vertical.
Microarray works on the same technology as PCR, and RT-PCRs, which works on a much grander scale where instead of screening one, two or maybe 20 genes, it screens thousands of genes at the same.

How does Microarray Test work?

Each spot on a microarray contains multiple identical strands of DNA.
The DNA sequence on each spot is unique.
Each spot represents one gene.
Thousands of spots are arrayed in orderly rows and columns on a solid surface (usually glass).
The precise location and sequence of each spot are recorded in a computer database.
Microarrays can be the size of a microscope slide, or even smaller.
There are usually 46 chromosomes in each of our cells, arranged in 23 pairs.

What information will the CMA test provide?

No copy number variant is found- This is the most common result
A copy number variant is found which does not usually cause any health or developmental concern
A copy number variant is found that explains the health or developmental concern.
A copy number variant is found but its impact on health or development is unclear
A copy number variant is found that contains a gene or genes unrelated to the developmental or health concerns, but which could potentially cause other health problems in the future

How does Microarray Test work?

Each spot on a microarray contains multiple identical strands of DNA.
The DNA sequence on each spot is unique.
Each spot represents one gene.
Thousands of spots are arrayed in orderly rows and columns on a solid surface (usually glass).
The precise location and sequence of each spot are recorded in a computer database.
Microarrays can be the size of a microscope slide, or even smaller.
There are usually 46 chromosomes in each of our cells, arranged in 23 pairs.

What is the cost of CMA test?

CMA Test costs 22000 Rs

How many days does it take for reports?

Reports take 21 working days

What are the different types of Microarray?

Microarray mutation analysis: For this analysis, the researchers use gDNA. The genes might differ from each other by as little as a single nucleotide base.
Microarray gene expression analysis: In this experimental setup, the cDNA derived from the mRNA of known genes is immobilized. The sample has genes from both the normal as well as the diseased tissues.
Comprehensive Genomic analysis: It is used for the identification of the increase or decrease of the important chromosomal fragments harbouring genes involved in a disease.
Chromosomal microarray analysis (CMA) is a technology used for the detection of clinically significant microdeletions or duplications, with high sensitivity for submicroscopic aberrations.
“Microarray” refers to a microchip-based testing platform that allows high-volume, automated analysis of many pieces of DNA at once. CMA chips use labels or probes that bind to specific chromosome regions. Computer analysis is used to compare a patient's genetic material to that of a reference sample.
CMA's can be used for a wide variety of purposes, from Product of Conception (POC) analysis to various neurological conditions.

They are the first-tier test for individuals with: Developmental disabilities

Autism spectrum disorders
No test can rule out all genetic diseases. Some types of variants require a different test, and some regions are technically difficult to isolate and analyze.

CMA does not detect:

Small changes in the sequence of single genes (point mutations)

Tiny duplications and deletions of DNA segments within a single gene (Fragile X syndrome, for example)
CMA testing may be a gateway to getting more help for families of children with previously undiagnosed conditions. A variant found on CMA may not only provide a long-awaited explanation for a patient's clinical findings.
Chromosomal microarray (CMA) testing looks for extra (duplicated) or missing (deleted) chromosomal segments, sometimes called copy number variants (CNVs). These include:

Microdeletions and microduplications of chromosome segments, which are too small to see under a microscope but may contain multiple genes

Most abnormalities of chromosome number (trisomy, monosomy, etc.), including Down syndrome

Most unbalanced rearrangements of chromosome structure (translocations, etc.)
Chromosomal Microarray costs 22000
Reports will take 3 weeks

Feel Free to contact us for any genetic DNA test enquires

For any inquiries relating to Chromosomal Microarray Test services feel free to speak to our certified genetic counsellors personally by call us during business hours. All Conversation is 100% confidential and Private.

Head office address:

DNA Diagnostics 204 2nd Floor GS towers Himayat Nagar Hyderabad 500029 India

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(040) 49171772

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